Side Effects of TRT Treatment

If a man’s body doesn’t produce enough testosterone for some reason, testosterone replacement therapy is needed. Let’s consider how TRT can affect the man’s body.

Side effects related to the type of medicine


Medicines for low testosterone treatment typically have the form of tablets, gels, plasters, intramuscular injections, or T-pellets. Each of them can have side effects:

  • Pills must be taken every day. This requires a high level of self-control, so people often omit taking medicine, and their hormone level decreases.
  • Injections don’t provide a stable entry of hormones into the blood. Immediately after the shot, it is high, and then gradually falls. Due to this, a man’s mood and libido can jump up and down.
  • T-pellets are injected under the skin through a short incision on the thigh. Irritation and itching may occur at this spot.

Symptoms caused by TRT therapy


Usually, men face side effects at the beginning of treatment. Sometimes, it is not possible to choose the correct dose right away, so the doctor constantly monitors how the patient’s body reacts.

Due to treatment, the number of red blood cells may increase. This can be dangerous, so your doctor will take regular blood tests.

Other side effects of TRT treatment:

  • Low sperm count, due to which a man may have problems with fertilization;
  • Apnea;
  • Reduction of testicles;
  • Acne and oily skin;
  • Breast augmentation. It can happen if the amount of testosterone is excessive. Then, it turns into estradiol and estrogen, which are known as “female hormones.”

People who had a heart attack previously should be cautious with hormones. Some studies show that TRT reduces the risk of cardiovascular diseases, while others show that patients can have repeat heart attacks.

TRT is a complex task and requires constant control. Testosterone clinic in Auburn selects treatment and helps men improve their health. Here, you can get support and all the necessary examinations.

So, it’s essential to understand that TRT therapy is not suitable for everyone. It may not be safe for men with prostate or breast cancer, high red blood cell count, sleep apnea, or heart problems. Therefore, it’s crucial to have a thorough medical checkup before beginning TRT therapy.

Some of the side effects of TRT can be managed by adjusting the dosage or switching to a different form of treatment. For example, if a man experiences acne and oily skin, the doctor may recommend a lower dose or a different medication.

It’s also important to note that TRT therapy should not be stopped suddenly. Abruptly stopping treatment can cause a hormonal imbalance, leading to mood swings, fatigue, and other unpleasant symptoms. Therefore, it’s essential to follow the doctor’s instructions and gradually reduce the dosage of testosterone if necessary.


In conclusion, TRT therapy can be an effective treatment for men with low testosterone levels. However, it’s important to understand the potential side effects and to work closely with a doctor to monitor the treatment’s effects on the body. With proper care and management, TRT can help men improve their quality of life and overall health.